Moscow University
Anthropology
Bulletin
Anthropology
Bulletin
1) Bryansk Pathoanatomical Institute; 2) Bryansk State University named after Academician I.G. Petrovskiy
Korsakov A.V., e-mail: korsakov_anton@mail.ru; Troshin V.P., e-mail: vptbr32@yandex.ru; Mikhalev V.P., e-mail: korsakov_anton@mail.ru; Zhilin A.V., e-mail: patanat32@gmail.com; Zhilina O.V., e-mail: patanat32@gmail.com; Vorobyova D.A., e-mail: patanat32@gmail.com; Korotkova N.S., e-mail: patanat32@gmail.com
Research objective. To define the influence of a complex of environmental technogenic factors on frequency of cytogenetic abnormalities in buccal epithelium of children of younger school age (on the materials from the Bryansk region). Materials and methods. Comparative evaluation of frequency of cytogenetic abnormalities in children (by micronuclear test in buccal epithelium) in ecologically unfavorable territories of the Bryansk region with various density of toxic (from 1.7 to 171.6 kg/per head/years), radioactive (from 10.7 to 504.3 kBc/m2 on 137Сs) substances and the combined pollution of environment is presented. Research of the cytogenetic status of 7-9 years old children was conducted by the micronuclear method and nuclear anomalies in exfoliative cells of humans [Stich et al., 1981]. In spring of 2011 in 242 children of 7-9 years old (123 boys and 119 girls) samples of buccal epithelium were taken. From each child from 500 to 1,500 cells were studied, with the following recalculation to 1000 cells (‰). In total 237,000 cells were analyzed. Results and discussion. Statistically significant adverse changes in the cytogenetic status of children living in the conditions of high-toxic or radioactive pollution, and, especially, combined chemical and radiation pollution, were expressed in raised frequency of cells containing two nucleus, and cells with kariopycnosis and kariolisis. Conclusions. The greatest statistically significant adverse changes of the cytogenetic status are registered in boys and girls living in the territories of combined radioactive-toxic pollution.
Ecological problems, average annual toxic loadings, density of radioactive pollution, buccal epithelium, cytogenetic abnormalities, micronuclear test
Цит.: Korsakov A.V., Troshin V.P., Mikhalev V.P., Zhilin A.V., Zhilina O.V., Vorobyova D.A., Korotkova N.S. Influence of complex of technogenic environmental factors on frequency of cytogenetic abnormalities in buccal epithelium of children of younger school age // Moscow University Anthropology Bulletin (Vestnik Moskovskogo Universiteta. Seria XXIII. Antropologia), 2012; 1/2012; с. 110-118
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