1) Federal state budgetary scientific Institution «Research Centre for Medical Genetics» Moskvorechie, 1, Moscow, 115522, Russia; 2) Science federal state institution «Federal scientific center of hygiene of F.F. Erisman» Federal Service for the Oversight of Consumer Protection and Welfare, Mytischi; 3) Municipal Budgetary Health Care setting «Habezskaya central district hospital», Habez, Karachai-Cherkess Republic; 4) Pirogov Russian National Research Medical University, Ostrovitianov str. 1, Moscow, 117997, Russia
El’chinova Galina Iv., PhD, DSc.; ORCID ID: 0000-0003-3665-982X; elchinova@med-gen.ru; Rеvаzоvа Yu.А.: e-mail: revazova013@gmail.com; Makaov A.Kh.: e-mail: makaov@yandex.ru; Zinchenko Rena Ab., PhD, DSc., professor; ORCID ID: 0000-0003-3586-3458; renazinchenko@mail.ru.
The complex medical populational genetical study of polyethnic Carachay-Cherkesia population carried out by genetic epidemiology laboratory of Research Centre for Medical Genetics since 2013. The work has been taken place in different regions of Russia by Protocol developed in the laboratory more than over thirty years. The Prоtоkоl includes survey of population by mobile team of medical specialists, the molecular-genetic verification of the diagnosis, obtaining population-genetic data from biological (blood) and non-biological sources of information (voters lists, marriage records, demographic questionaries), statistical processing of data. The Nogais are the Turkic speaking people and the direct descendants of Kipchaks. The Nogais densely are living in Nogais district of Karachai-Cherkesia, 76,7% of the population of district are the Nogais. The standard population-genetic characteristics of Nogais district was calculated (ethnic marriage assortativeness H, the intensity of metisation, the endogamy index, values of the random inbreeding of Wright, the parameters of Barrai, isolation by distance parameters of Malecot, create schemas of surname and inbreed landscape) based on 1522 surnames and 1115 marriage records for 1990-2000. Ethnic marriage assortativeness Н=1,06 (for Nogais, the main ethnic group in district), for their neighbor H is more highly: Н=30,3 (the Аbazins), Н=25 (the Karachais), Н=6,2 (the Russians), Н=46,2 (the Tаtаrs), Н=14,3 (the Cirkasians). A substantial mismatch between the observed and the expected number of both interethnic and intraethnic marriages is noticed. The intensity of metisation 21,9% for rural Nogais and 79,3% for sitizens (Cherkessk). The Population is not panmixia according ethnic sign. The endogamy index is iow in auls (0,05–0,41) and in district (0,56). The significance of random inbreeding Fst in district population is 0,0024, the local inbreeding а – 0,00039. The values of both estimations of inbreeding in rural settlement (1–2 auls) have been calculated too. The coefficient of linear correlation between two estimations of inbreeding (random and local), recieved by different method from different (the frequencies of surname distribution and lenghs of marriage migration), positive and significant (r=0,62±0,45). The matrix of surname distance detects positive and significant correlation with matrix of square root from gеоgrаphic distance (r=0,62±0,28). The correlation between matrix, from which schemas of surname and inbreed landscape had been created, is r=0,73±0,24. The degree of isolation by distance b the expected negative correlated with index of migration (r=-0,94±0,19) and entropy (r=-0,82±0,33). The significant end expected by sing values of coefficient of correlation between reсieved characteristics let us speak about suitability the Nogais surnames as biology marker in population-genetic researches.
Nogais, random inbreeding, isolation by distance, endogamy, marriage ethnic assortativeness
Цит.: Еl’chinоvа G.I., Rеvаzоvа Yu.А., Makaov A.Kh.-M., Zinchеnkо R.А. Pоpulatiоn and gеnетiс chаrаcтеrisтic of nоgаis in Kаrаchаy-Chеrкеsia (by datas abоut the surname distribution and marriage migration) // Moscow University Anthropology Bulletin (Vestnik Moskovskogo Universiteta. Seria XXIII. Antropologia), 2016; 1/2016; с. 109-115
Download text