Lomonosov Moscow State University, Anuchin Research Institute and Museum of Anthropology, Mokhovaya st., 11, Moscow, 125009, Russia
Bondareva E.A., Ph.D., ORCID ID: 0000-0003-3321-7575, e-mail: Bondareva.E@gmail.com
Fat accumulation is influenced by both genetic and environmental factors. One of the best studied gene polymorphism associated with excessive weight is the FTO gene. Results of the study of Т/А polymorphism (rs9939609) in FTO gene are presented in the paper. The sample included 321 young males (mean age – 23.0±5.8 years). Among them, sportsmen of high qualification (127 individuals), military personnel with high sports qualifications (102 individuals), and control sample (92 individuals). It was shown that fat accumulation is associated with AA genotype – a homozygous state of a mutant allele. At the same time the presence of at least one of the base allele T significantly decrease the risk to excessive fat accumulation.
biological anthropology, molecular genetics, obesity, overweight, FTO gene, спортсмены, young males
Цит.: Bondareva E.A. T/A polymorphism of FTO gene is associated with overweight // Moscow University Anthropology Bulletin (Vestnik Moskovskogo Universiteta. Seria XXIII. Antropologia), 2010; 4/2010; с. 65-69
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